The review article assocaited with Josh’s work with PZ Cussons has been published. Josh worked on on the KTP project Understanding the physiological processes of the DHA skin colouring mechanism.
Our 1st paper of 2022 comes from Dom’s research. In this paper, Dom shows how the thermoresponsive and degradation behaviour of nanogels can be tuned by using a core-shell structure.
Cameron’s first paper is now published. Cameron prepared hydrophobically modified drug analogues and used these to produce nanoparticles. These particles displayed high drug loading and the LogP of the compound controlled NP formation.
Nancy’s second paper has recently been published. In this work, Nancy shows a new and simple way of formulating a poorly soluble compound like curcumin to give a solid that can be dispersed to give nanoparticles. This approach allowed the curcumin to display similar biological properties to solubilised curcumin but without the need for any solvent. See the full article here.
Our review article on nanoparticles that show multi-stimuli-responsive aggregation behaviour is now online in Nanoscale. This article came out of Luke Johnson’s MSc student’s project, with support from Dom and Edyta carried out during the lockdown. I think that this is a great output (especially under the circumstances) and is credit to the work from Luke, Dom and Edyta.
The article is available here.
In this work, Jess investigated the effect of the structure of poloxamer stabilisers on the polarity inside solid lipid nanoparticles. This understanding will assist the selection of stabilisers and may potentially allow increased drug loading in solid lipid nanoparticles. See the full article here.
In this paper, Edyta shows how asymmetric-flow field-flow fractionation can be used to characterise the internal structure of nanogels. See the full article here.
Her work investigates the development of lipid-polymer hybrid nanoparticles for the delivery of HIV drugs. She shows that the lipid coating on nanoparticles plays an important role in improving biological uptake. See online here.
Her work investigates the use of layer-by-layer modification of nanoparticles to achieve stimuli responsive drug release. See online here.
See online here