{"id":85,"date":"2017-03-01T16:46:56","date_gmt":"2017-03-01T16:46:56","guid":{"rendered":"http:\/\/www.mcdonaldlab.co.uk\/?p=85"},"modified":"2017-03-01T16:46:56","modified_gmt":"2017-03-01T16:46:56","slug":"adams-paper-on-microgel-solid-drug-nanoparticle-nanocomposites-for-release-of-poorly-soluble-drugs-is-published-in-nanoscale","status":"publish","type":"post","link":"https:\/\/www.mcdonaldlab.synology.me\/wordpress\/2017\/03\/01\/adams-paper-on-microgel-solid-drug-nanoparticle-nanocomposites-for-release-of-poorly-soluble-drugs-is-published-in-nanoscale\/","title":{"rendered":"Adam\u2019s paper on microgel\/solid drug nanoparticle nanocomposites for release of poorly soluble drugs is published in Nanoscale"},"content":{"rendered":"\n\t\t\t\t\n<p> Adam\u2019s paper on the design of microgels as in situ forming implant (ISFI) for sustained drug delivery has been published in\u00a0<a href=\"https:\/\/web.archive.org\/web\/20170717095115\/http:\/\/pubs.rsc.org\/en\/content\/articlelanding\/2017\/nr\/c6nr07858c\">Nanoscale<\/a>.\u00a0In this work, he developed dual-responsive microgels that would form well-defined aggregated when exposed to physiological temperature and ionic strength, avoiding any potential issues with aggregate formation in the needle. We found that the microgels could entrap up to 40 wt % of dug payload nanoparticles, offered tunable drug release exceeding 120 days and were not cytotoxic in vitro. <\/p>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Adam\u2019s paper on the design of microgels as in situ forming implant (ISFI) for sustained drug delivery has been published in\u00a0Nanoscale.\u00a0In this work, he developed dual-responsive microgels that would form well-defined aggregated when exposed to physiological temperature and ionic strength, avoiding any potential issues with aggregate formation in the needle. We found that the microgels &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.mcdonaldlab.synology.me\/wordpress\/2017\/03\/01\/adams-paper-on-microgel-solid-drug-nanoparticle-nanocomposites-for-release-of-poorly-soluble-drugs-is-published-in-nanoscale\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Adam\u2019s paper on microgel\/solid drug nanoparticle nanocomposites for release of poorly soluble drugs is published in Nanoscale&#8221;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[5],"tags":[],"_links":{"self":[{"href":"https:\/\/www.mcdonaldlab.synology.me\/wordpress\/wp-json\/wp\/v2\/posts\/85"}],"collection":[{"href":"https:\/\/www.mcdonaldlab.synology.me\/wordpress\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.mcdonaldlab.synology.me\/wordpress\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.mcdonaldlab.synology.me\/wordpress\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.mcdonaldlab.synology.me\/wordpress\/wp-json\/wp\/v2\/comments?post=85"}],"version-history":[{"count":0,"href":"https:\/\/www.mcdonaldlab.synology.me\/wordpress\/wp-json\/wp\/v2\/posts\/85\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.mcdonaldlab.synology.me\/wordpress\/wp-json\/wp\/v2\/media?parent=85"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.mcdonaldlab.synology.me\/wordpress\/wp-json\/wp\/v2\/categories?post=85"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.mcdonaldlab.synology.me\/wordpress\/wp-json\/wp\/v2\/tags?post=85"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}